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File:Schematic representation of selective migration of MSCs to areas of tissue injury and tumours where they contribute to tissue repair and tumour-associated stroma formation..jpg

Schematic_representation_of_selective_migration_of_MSCs_to_areas_of_tissue_injury_and_tumours_where_they_contribute_to_tissue_repair_and_tumour-associated_stroma_formation..jpg ‎(600 × 322 pixels, file size: 70 KB, MIME type: image/jpeg)

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English: (1) Lung injury stimulates MSC activation via interaction of SDF-1 with its receptor CXCR4. Acting in an autocrine fashion SDF-1 causes increased migration, survival and proliferation of MSCs. (2) Activated MSCs migrate to areas of injury and tumour in response to SDF-1.
Date Published September 30, 2008.
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StemBook Figure 1 Schematic representation of selective migration of MSCs to areas of tissue injury and tumours where they contribute to tissue repair and tumour-associated stroma formation.

  • Sage, E.K., Loebinger, M.R., Polak, J. and Janes, S.M., The role of bone marrow-derived stem cells in lung regeneration and repair (September 30, 2008), StemBook, ed. The Stem Cell Research Community, StemBook, doi/10.3824/stembook.1.20.1, http://www.stembook.org.
Author Sage, E.K., Loebinger, M.R., Polak, J. and Janes, S.M., The role of bone marrow-derived stem cells in lung regeneration and repair (September 30, 2008), StemBook, ed. The Stem Cell Research Community, StemBook, doi/10.3824/stembook.1.20.1, http://www.stembook.org.
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