File:Sequential sections of colon epithelium near a cancer showing reduced or absent expression of PMS2 (A), ERCC1 (B) and ERCC4 (C).tif
Size of this JPG preview of this TIF file: 800 × 188 pixels. Other resolutions: 320 × 75 pixels | 1,997 × 469 pixels.
Original file (1,997 × 469 pixels, file size: 2.66 MB, MIME type: image/tiff)
File information
Structured data
Captions
Summary
editDescriptionSequential sections of colon epithelium near a cancer showing reduced or absent expression of PMS2 (A), ERCC1 (B) and ERCC4 (C).tif |
English: Sequential sections of a segment of colon epithelium near a colorectal cancer showing reduced or absent expression of PMS2 (A), ERCC1 (B) and ERCC4 (C) in the colon crypts. This tissue segment is from a histologically normal area of a colon resection of a male patient who had an adenocarcinoma in the sigmoid colon. For PMS2 (A), there is absent expression in cell nuclei of the crypt body, the crypt neck and the colonic lumen surface for all epithelial cells. For ERCC1 (B), there is reduced expression in most of the cell nuclei of the crypts, but there is high expression in cell nuclei at the neck of the crypts and in the adjacent colonic lumen surface. For ERCC4 (XPF) (C), there is absent expression in most of the cell nuclei of the crypts and in the colonic lumen in this area of tissue, but detectable expression at the neck of some crypts. The reductions or absence of expression of these DNA repair genes in this tissue appears to be due to epigenetic repression.[1] Original image, also in a publication.[1] |
Date | |
Source | Own work |
Author | Chaya5260 |
Licensing
editI, the copyright holder of this work, hereby publish it under the following license:
This file is licensed under the Creative Commons Attribution-Share Alike 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 00:15, 6 August 2015 | 1,997 × 469 (2.66 MB) | Chaya5260 (talk | contribs) | User created page with UploadWizard |
You cannot overwrite this file.
File usage on Commons
There are no pages that use this file.
File usage on other wikis
The following other wikis use this file:
Metadata
This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.
Width | 1,997 px |
---|---|
Height | 469 px |
Bits per component |
|
Compression scheme | LZW |
Pixel composition | RGB |
Number of components | 3 |
Number of rows per strip | 8 |
Horizontal resolution | 300 dpi |
Vertical resolution | 300 dpi |
Data arrangement | chunky format |