File:Spectrum of pluripotency in the human embryo.jpg
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| Description | Figure 3. Spectrum of pluripotency in the human embryo. On embryonic day 6 (E6), the human blastocyst is pre-implanted, with probable naïve pluripotency. During implantation (E7-8), two lineages emerge in human embryos: the extra-embryonic mesoderm from the visceral endoderm (hypoblast) and the amniotic epithelium from the epiblast. On days 9–10, the amniotic cavity arises, while the post-implanted epiblast still expresses genes related to pluripotency but is no longer in the naïve state. It has been suggested that human primordial germ cell (hPGC) specification occurs at around E11-12, but also both lineages can arise from the same population that possesses germinal pluripotency. It is likely that the human epiblast, similar to the mouse, acquires an anterior-posterior regionalization with different subtypes of pluripotency biased toward specific lineages. On day 16, the onset of human gastrulation is preceded by the appearance of the primitive streak in the posterior region of the epiblast |
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| Source | https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2021.676998/full Ávila-González D, Portillo W, García-López G, Molina-Hernández A, Díaz-Martínez NE and Díaz NF (2021) Unraveling the Spatiotemporal Human Pluripotency in Embryonic Development. Front. Cell Dev. Biol. 9:676998. doi: 10.3389/fcell.2021.676998 |
| Author | Ávila-González D, Portillo W, García-López G, Molina-Hernández A, Díaz-Martínez NE and Díaz NF |
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© 2021 Ávila-González, Portillo, García-López, Molina-Hernández, Díaz-Martínez and Díaz. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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| current | 00:46, 3 September 2024 | | 1,950 × 1,006 (324 KB) | Rasbak (talk | contribs) | {{Information |description=Figure 3. Spectrum of pluripotency in the human embryo. On embryonic day 6 (E6), the human blastocyst is pre-implanted, with probable naïve pluripotency. During implantation (E7-8), two lineages emerge in human embryos: the extra-embryonic mesoderm from the visceral endoderm (hypoblast) and the amniotic epithelium from the epiblast. On days 9–10, the amniotic cavity arises, while the post-implanted epiblast still expresses genes related to pluripotency but is no lon... |
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