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File:Structural basis for DNA binding by the PolD–PCNA complex.pdf

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Structural basis for DNA binding by the PolD–PCNA complex

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English: a View of the DP2 clamp-1 (light blue) and clamp-2 (dark blue) domains surrounding one turn of the DNA duplex (orange). The two catalytic double-psi β-barrels DPBB-1 and DPBB-2 are represented in red and yellow, respectively. Template and primer strands are indicated by T and P, respectively. b Interaction with the PolD clamp causes a local distortion of the DNA (orange) compared with an ideal B-form DNA (white). The phosphates of the DNA duplexes are shown as spheres. c PCNA makes labile contacts with DNA. Focused classification on PCNA resulted in three 3D classes showing extra-densities between DNA and PCNA residues K84 and K86, which are underlined by arrows.[1]
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Source https://doi.org/10.1038/s41467-020-15392-9
Author Clément Madru, Ghislaine Henneke, Pierre Raia, Inès Hugonneau-Beaufet, Gérard Pehau-Arnaudet, Patrick England, Erik Lindahl, Marc Delarue, Marta Carroni & Ludovic Sauguet

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This file is licensed under the Creative Commons Attribution 4.0 International license.
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current23:32, 4 April 2020Thumbnail for version as of 23:32, 4 April 20201,012 × 600 (1.4 MB)Rob Hurt (talk | contribs)Uploaded a work by Clément Madru, Ghislaine Henneke, Pierre Raia, Inès Hugonneau-Beaufet, Gérard Pehau-Arnaudet, Patrick England, Erik Lindahl, Marc Delarue, Marta Carroni & Ludovic Sauguet from https://doi.org/10.1038/s41467-020-15392-9 with UploadWizard

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