File:Tofacitinib,JAK.png
No higher resolution available.
Tofacitinib,JAK.png (386 × 262 pixels, file size: 24 KB, MIME type: image/png)
Captions
Captions
Add a one-line explanation of what this file represents
Summary edit
| Description |
English: Binding of tofacitinib to JAK. It occurs in the ATP binding site, through a hydrogen bond with the hinge-region of the kinase. The piperidine methyl group binds in a lipophilic pocket in the C-terminal lobe at the base of the active site. The cyanoacetyl group on the piperidine ring binds in the glycine-rich loop (P-loop). |
| Date | |
| Source | Own work |
| Author | Pharmstudice |
Licensing edit
I, the copyright holder of this work, hereby publish it under the following license:
This file is licensed under the Creative Commons Attribution-Share Alike 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 11:14, 30 September 2016 | | 386 × 262 (24 KB) | Pharmstudice (talk | contribs) | User created page with UploadWizard |
You cannot overwrite this file.
File usage on Commons
There are no pages that use this file.
