Wikimedia Commons

File:TopBP1 oligomerization and transcriptional regulation.png

Original file ‎(2,207 × 905 pixels, file size: 253 KB, MIME type: image/png)

Captions

Captions

TopBP1 mediated transcriptional regulation of E2F-1 target genes.

Summary

edit
Description
English: Following DNA damage, TopBP1 is phosphorylated by Akt and self oligomerizes at the BRCT7/8 domains. Oligomeric TopBP1 can bind to E2F-1 and recruit chromatin remodeling machinery (e.g. HDAC) to repress E2F-1 driven gene expression.
Date
Source Own work
Author Cpt01

Licensing

edit
I, the copyright holder of this work, hereby publish it under the following license:
w:en:Creative Commons
attribution share alike
This file is licensed under the Creative Commons Attribution-Share Alike 4.0 International license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current22:43, 28 November 2022Thumbnail for version as of 22:43, 28 November 20222,207 × 905 (253 KB)Cpt01 (talk | contribs)reformatted shapes
22:45, 27 November 2022Thumbnail for version as of 22:45, 27 November 20222,207 × 905 (79 KB)Cpt01 (talk | contribs)Uploaded own work with UploadWizard

You cannot overwrite this file.

There are no pages that use this file.

File usage on other wikis

The following other wikis use this file:

Metadata

This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.

Retrieved from "https://commons.wikimedia.org/w/index.php?title=File:TopBP1_oligomerization_and_transcriptional_regulation.png&oldid=710668414"