English: Two invasion pathways of Entomopathogenic fungi in mosquitoes: cuticle and digestive tract routes. Entomopathogenic fungi infect mosquito adults, eggs, and pupae through contact with the cuticle. Larvae can be infected through both the cuticle and digestive tract routes. Fungal conidia attach to the cuticle and germinate to form germ tubes, which either penetrate the cuticle directly or develop appressoria at the end of the germ tubes to penetrate the cuticle. Once the cuticle is breached, hyphal bodies rapidly developed in the hemolymph of adult. In eggs, the growth of hyphal bodies inside can cause incomplete embryogenesis or spontaneous premature eclosion. Toxic metabolites can disrupt the balance of microorganisms in the midgut and accelerate mosquito mortality. In pupae, cuticle infection can lead to death or accelerated molting. In larvae, similar to adults, conidia can infect through the cuticle and enter the hemolymph. Additionally, conidia can be ingested and grow within the digestive tract. The fungus can penetrate the peritrophic membrane of the midgut to enter the hemolymph.