File:Vaccines-09-00065-g001.webp

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mRNA lipid nanoparticle structure.

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Description
English: mRNA lipid nanoparticle structure. Recent studies using cryoelectron microscopy, small-angle neutron scattering and small-angle X-ray scattering have shown that the mRNA lipid nanoparticle includes low copy numbers of mRNA (1–10) and that the mRNA is bound by the ionizable lipid that occupies the central core of the LNP. The polyethylene glycol (PEG) lipid forms the surface of the lipid nanoparticle (LNP), along with DSPC, which is bilayer forming. Cholesterol and the ionizable lipid in charged and uncharged forms can be distributed throughout the LNP.
Date
Source Buschmann, M.D.; Carrasco, M.J.; Alishetty, S.; Paige, M.; Alameh, M.G.; Weissman, D. Nanomaterial Delivery Systems for mRNA Vaccines. Vaccines 2021, 9, 65. https://doi.org/10.3390/vaccines9010065
Author Michael D. Buschmann, Manuel J. Carrasco, Suman Alishetty, Mikell Paige, Mohamad G. Alameh, and Drew Weissman

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current09:31, 15 August 2021Thumbnail for version as of 09:31, 15 August 20211,516 × 1,728 (1.44 MB)Guest2625 (talk | contribs)Uploaded a work by Michael D. Buschmann, Manuel J. Carrasco, Suman Alishetty, Mikell Paige, Mohamad G. Alameh, and Drew Weissman from Buschmann, M.D.; Carrasco, M.J.; Alishetty, S.; Paige, M.; Alameh, M.G.; Weissman, D. Nanomaterial Delivery Systems for mRNA Vaccines. Vaccines 2021, 9, 65. https://doi.org/10.3390/vaccines9010065 with UploadWizard

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