Computer simulation is a valuable tool for the research of physics. These simulations can be especially valuable when there is experimental data available that can be used to validate the model. The main objective of this thesis is to determine whether a computer simulation model can accurately depict the experimentally determined fluid flow for a channel with a series of unique individual constrictions. The experimental data are derived from a scaled-up model of coronary blood flow with localized axisymmetric constrictions (or stenoses), representing an ideal case of atherosclerotic disease. This thesis provides the foundation for future study and simulation to develop a microelectromechanical device mounted on a stent capable of sensing and transmitting changes in blood flow characteristics and properties to an outside receiver for improved treatment of patients with atherosclerotic coronary artery disease.