File:ALS-Associated-TDP-43-Induces-Endoplasmic-Reticulum-Stress-Which-Drives-Cytoplasmic-TDP-43-pone.0081170.s001.ogv
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ALS-Associated-TDP-43-Induces-Endoplasmic-Reticulum-Stress-Which-Drives-Cytoplasmic-TDP-43-pone.0081170.s001.ogv (Ogg Theora video file, length 7.0 s, 360 × 360 pixels, 124 kbps, file size: 106 KB)
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editDescriptionALS-Associated-TDP-43-Induces-Endoplasmic-Reticulum-Stress-Which-Drives-Cytoplasmic-TDP-43-pone.0081170.s001.ogv |
English: Association of 218–414 TDP-43-mCherry inclusions with the Golgi apparatus. Neuro2a cells were transfected with the 218–414 TDP-43-mCherry construct, and treated with 10 µM MG132 for 24 h starting at 24 h post-transfection. Cells were processed for immunocytochemistry against GM130 (green) and serial z-stack images were taken at 0.50 µm intervals using confocal microscopy and post-processed using Olympus Fluoview v2.0 software. mCherry fluorescence is shown in red and nuclei (Hoechst dye) are shown in blue. Scale bar represents 10 µm. |
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Source | Video S1 from Walker A, Soo K, Sundaramoorthy V, Parakh S, Ma Y, Farg M, Wallace R, Crouch P, Turner B, Horne M, Atkin J (2013). "ALS-Associated TDP-43 Induces Endoplasmic Reticulum Stress, Which Drives Cytoplasmic TDP-43 Accumulation and Stress Granule Formation". PLOS ONE. DOI:10.1371/journal.pone.0081170. PMID 24312274. PMC: 3843686. | ||
Author | Walker A, Soo K, Sundaramoorthy V, Parakh S, Ma Y, Farg M, Wallace R, Crouch P, Turner B, Horne M, Atkin J | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 19:27, 10 December 2013 | 7.0 s, 360 × 360 (106 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Walker A, Soo K, Sundaramoorthy V, Parakh S, Ma Y, Farg M, Wallace R, Crouch P, Turner B, Horne M, Atkin J |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
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Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2013 |