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File:Brusatol-provokes-a-rapid-and-transient-inhibition-of-Nrf2-signaling-and-sensitizes-mammalian-cells-mmc2.ogv

Brusatol-provokes-a-rapid-and-transient-inhibition-of-Nrf2-signaling-and-sensitizes-mammalian-cells-mmc2.ogv ‎(Ogg multiplexed audio/video file, Theora/Vorbis, length 1 min 52 s, 640 × 480 pixels, 448 kbps overall, file size: 5.96 MB)

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English: Video 1 Real-time imaging of Nrf2-Venus in SK-N-AS cells exposed to CDDO-Me and brusatol. An SK-N-AS cell line, stably expressing Nrf2-Venus under control of the endogenous human Nrf2 promoter, was exposed to 100 nM CDDO-Me at 0 h, followed by 300 nM brusatol at 1 h. Nrf2-Venus expression was recorded at 2 min intervals by confocal microscopy. Video uploaded separately..
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Source Video file from Olayanju A, Copple I, Bryan H, Edge G, Sison R, Wong M, Lai Z, Lin Z, Dunn K, Sanderson C, Alghanem A, Cross M, Ellis E, Ingelman-Sundberg M, Malik H, Kitteringham N, Goldring C, Park B (2015). "Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity—implications for therapeutic targeting of Nrf2". Free Radical Biology & Medicine. DOI:10.1016/j.freeradbiomed.2014.11.003. PMID 25445704. PMC: 4291150.
Author Olayanju A, Copple I, Bryan H, Edge G, Sison R, Wong M, Lai Z, Lin Z, Dunn K, Sanderson C, Alghanem A, Cross M, Ellis E, Ingelman-Sundberg M, Malik H, Kitteringham N, Goldring C, Park B
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current02:18, 2 November 20161 min 52 s, 640 × 480 (5.96 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 480P 233 kbps Completed 11:36, 20 August 2018 1 min 10 s
Streaming 480p (VP9) 230 kbps Completed 14:02, 12 January 2024 1.0 s
VP9 360P 128 kbps Completed 11:36, 20 August 2018 1 min 11 s
Streaming 360p (VP9) 125 kbps Completed 22:12, 17 January 2024 1.0 s
VP9 240P 70 kbps Completed 11:36, 20 August 2018 45 s
Streaming 240p (VP9) 67 kbps Completed 14:47, 16 December 2023 1.0 s
WebM 360P 512 kbps Completed 02:20, 2 November 2016 1 min 50 s
Streaming 144p (MJPEG) 705 kbps Completed 10:03, 1 November 2023 3.0 s
Stereo (Opus) 1 kbps Completed 16:11, 16 November 2023 1.0 s
Stereo (MP3) 128 kbps Completed 15:41, 30 October 2023 2.0 s

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