File:Chemotaxis-in-Densely-Populated-Tissue-Determines-Germinal-Center-Anatomy-and-Cell-Motility-A-New-pone.0027650.s009.ogv
Chemotaxis-in-Densely-Populated-Tissue-Determines-Germinal-Center-Anatomy-and-Cell-Motility-A-New-pone.0027650.s009.ogv (Ogg Theora video file, length 25 s, 324 × 424 pixels, 3.24 Mbps, file size: 9.68 MB)
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editDescriptionChemotaxis-in-Densely-Populated-Tissue-Determines-Germinal-Center-Anatomy-and-Cell-Motility-A-New-pone.0027650.s009.ogv |
English: Primary follicle homeostasis. The video begins with an empty BTU. As time progresses, lymphocytes enter the tissue. Colors: naive B-cells (red) and naive CD4/8. Driven by chemotaxis, naive B-cells migrate to the FDC populated follicle in response to CXCL13, while memory B-cells and T-cells remain in the FRC populated extrafollicular region in response to CCL21/19. Cells remain in the BTU for ∼12–24 hours, at which point they change their chemotaxis preference to the exit chemokine S1P and actively leave via efferent lymphatics at the bottom of the tissue (exiting naive B-cells shown in yellow). |
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Source | Video S2 from Hawkins J, Jones M, Plassmann P, Thorley-Lawson D (2011). "Chemotaxis in Densely Populated Tissue Determines Germinal Center Anatomy and Cell Motility: A New Paradigm for the Development of Complex Tissues". PLOS ONE. DOI:10.1371/journal.pone.0027650. PMID 22145018. PMC: 3228727. | ||
Author | Hawkins J, Jones M, Plassmann P, Thorley-Lawson D | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 03:55, 14 November 2012 | 25 s, 324 × 424 (9.68 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Hawkins J, Jones M, Plassmann P, Thorley-Lawson D |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | Primary follicle homeostasis. The video begins with an empty BTU. As time progresses, lymphocytes enter the tissue. Colors: naive B-cells (red) and naive CD4/8. Driven by chemotaxis, naive B-cells migrate to the FDC populated follicle in response to CXCL13, while memory B-cells and T-cells remain in the FRC populated extrafollicular region in response to CCL21/19. Cells remain in the BTU for ?12?24 hours, at which point they change their chemotaxis preference to the exit chemokine S1P and actively leave via efferent lymphatics at the bottom of the tissue (exiting naive B-cells shown in yellow). |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2011 |