File:Continuum-Molecular-Simulation-of-Large-Conformational-Changes-during-Ion–Channel-Gating-pone.0020186.s007.ogv
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English: A trajectory of conformational changes during gating, when the membrane potential is increased from a resting potential of −100 mV to a depolarized potential of +60 mV. The two orange helical segments are the S4–S3 complex. At −100 mV they are at their most downward location (deep resting). In response to increase of membrane potential to +60 mV they move upward (with slight rotation) to the intermediate resting state. They stay at that state for a while and then move upward along with a noticeable rotation to the activated state. Legend in upper right corner shows the voltage sensor state and in upper left corner the membrane potential. |
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| Source | Movie S3 from Nekouzadeh A, Rudy Y (2011). "Continuum Molecular Simulation of Large Conformational Changes during Ion–Channel Gating". PLOS ONE. DOI:10.1371/journal.pone.0020186. PMID 21625456. PMC: 3098872. | ||
| Author | Nekouzadeh A, Rudy Y | ||
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 09:26, 21 November 2012 | 18 s, 1,280 × 720 (1.89 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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