File:De-Novo-Generation-of-Infectious-Prions-In-Vitro-Produces-a-New-Disease-Phenotype-ppat.1000421.s005.ogv
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De-Novo-Generation-of-Infectious-Prions-In-Vitro-Produces-a-New-Disease-Phenotype-ppat.1000421.s005.ogv (Ogg Theora video file, length 3 min 19 s, 320 × 240 pixels, 727 kbps, file size: 17.24 MB)
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editDescriptionDe-Novo-Generation-of-Infectious-Prions-In-Vitro-Produces-a-New-Disease-Phenotype-ppat.1000421.s005.ogv |
English: Shows a close-up of the behavioral activity of various animals. First, a hamster with clinical signs of the disease produced by PGP-h1 inoculation. Animal exhibit rough coat and clear motor problems including tremor of the head, wobbling gait, head bobbing. It also show a much reduced exploratory behavior and lack of interest for interacting with the object introduced in the cage. The second animal corresponds to a 263K sick hamster exhibiting the typical hyperactivity, motor impairments and aggressiveness. Finally for comparison purposes we show the behavior of a normal healthy hamster of similar age. |
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Source | Video S2 from Barria M, Mukherjee A, Gonzalez-Romero D, Morales R, Soto C (2009). "De Novo Generation of Infectious Prions In Vitro Produces a New Disease Phenotype". PLOS Pathogens. DOI:10.1371/journal.ppat.1000421. PMID 19436715. PMC: 2675078. | ||
Author | Barria M, Mukherjee A, Gonzalez-Romero D, Morales R, Soto C | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 12:40, 17 November 2012 | 3 min 19 s, 320 × 240 (17.24 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Barria M, Mukherjee A, Gonzalez-Romero D, Morales R, Soto C |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | Shows a close-up of the behavioral activity of various animals. First, a hamster with clinical signs of the disease produced by PGP-h1 inoculation. Animal exhibit rough coat and clear motor problems including tremor of the head, wobbling gait, head bobbing. It also show a much reduced exploratory behavior and lack of interest for interacting with the object introduced in the cage. The second animal corresponds to a 263K sick hamster exhibiting the typical hyperactivity, motor impairments and aggressiveness. Finally for comparison purposes we show the behavior of a normal healthy hamster of similar age. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2009-05 |