File:Disruption-of-Mitochondrial-DNA-Replication-in-Drosophila-Increases-Mitochondrial-Fast-Axonal-pone.0007874.s002.ogv
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Disruption-of-Mitochondrial-DNA-Replication-in-Drosophila-Increases-Mitochondrial-Fast-Axonal-pone.0007874.s002.ogv (Ogg Theora video file, length 5.3 s, 625 × 74 pixels, 536 kbps, file size: 349 KB)
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editDescriptionDisruption-of-Mitochondrial-DNA-Replication-in-Drosophila-Increases-Mitochondrial-Fast-Axonal-pone.0007874.s002.ogv |
English: Axonal transport of mitochondria in pol γ-α mutants (tam3/tam9). Bidirectional mitochondrial flux is elevated in tam3/tam9 mutants, but velocity of kinesin mediated anterograde transport is slower than control animals. Crawling third-instar larvae expressing mitoGFP were anesthetized with chloroform and imaged intact on a swept-field confocal microscope. Observations were made every 2 s on a single plane in a temperature controlled chamber set at 25°C. Transport was observed in the most medial segmental nerves close to the ventral nerve cord. This video is accelerated to 15X of normal speed. |
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Source | Video S2 from Baqri R, Turner B, Rheuben M, Hammond B, Kaguni L, Miller K (2009). "Disruption of Mitochondrial DNA Replication in Drosophila Increases Mitochondrial Fast Axonal Transport In Vivo". PLOS ONE. DOI:10.1371/journal.pone.0007874. PMID 19924234. PMC: 2773408. | ||
Author | Baqri R, Turner B, Rheuben M, Hammond B, Kaguni L, Miller K | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 02:51, 17 November 2012 | 5.3 s, 625 × 74 (349 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Baqri R, Turner B, Rheuben M, Hammond B, Kaguni L, Miller K |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
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Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2009 |