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File:Free-Fatty-Acid-Induced-PP2A-Hyperactivity-Selectively-Impairs-Hepatic-Insulin-Action-on-Glucose-pone.0027424.g006.jpg

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English: PP2A levels were upregulated in all major insulin target tissues while PP2A activity was upregulated in liver and muscle in severely insulin-resistant ZDF rats. (a) Hepatic, muscle and fat mRNA levels of the catalytic subunit of PP2A (Ppp2ca) and (b) hepatic and muscle PP2A activity were found to be significantly elevated in obese fa/fa ZDF rats compared to their lean Fa/Fa counterparts. Relative expression and fold change is relative to Fa/Fa expression or activity levels. Data are averages of real-time PCR results or PP2A activity measurements +/− std. error of the mean. n = 8 for fa/fa rats and n = 6 for Fa/Fa rats. * indicates p<0.05.
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Source Image file from Galbo T, Olsen G, Quistorff B, Nishimura E (2011). "Free Fatty Acid-Induced PP2A Hyperactivity Selectively Impairs Hepatic Insulin Action on Glucose Metabolism". PLOS ONE. DOI:10.1371/journal.pone.0027424. PMID 22087313. PMC: 3210172.
Author Galbo T, Olsen G, Quistorff B, Nishimura E
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current22:41, 7 May 2016Thumbnail for version as of 22:41, 7 May 2016455 × 384 (59 KB)Recitation-bot (talk | contribs)Automatic upload of media from: doi:10.1371/journal.pone.0027424

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