File:Kupffer-Cells-Hasten-Resolution-of-Liver-Immunopathology-in-Mouse-Models-of-Viral-Hepatitis-ppat.1002061.s009.ogv
Kupffer-Cells-Hasten-Resolution-of-Liver-Immunopathology-in-Mouse-Models-of-Viral-Hepatitis-ppat.1002061.s009.ogv (Ogg Theora video file, length 23 s, 320 × 238 pixels, 137 kbps, file size: 390 KB)
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editDescriptionKupffer-Cells-Hasten-Resolution-of-Liver-Immunopathology-in-Mouse-Models-of-Viral-Hepatitis-ppat.1002061.s009.ogv |
English: PGK-GFP 1.3.32 HBV chimeric mice in which KCs and circulating white blood cells express GFP (green) were subjected to liver intravital microscopy. The movie depicts periportal liver sinusoids in a representative mouse that was infused 15 minutes earlier with 108 rhodamine-labeled beads (red) and 5 minutes earlier with 106 Hoechst-labeled HBV-specific effector CD8 T cells (blue). The movie shows an example of a virus-specific effector CD8 T cell arresting in close proximity and transiently coming in contact with a KC. Analysis of 30 minutes movies derived from 6 independent chimeric mice showed 30% of visualized HBV-specific effector CD8 T cells interacting with KCs (mean interaction time of 5±1 second). Scale bar represents 50 µm. |
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Source | Video S1 from Sitia G, Iannacone M, Aiolfi R, Isogawa M, van Rooijen N, Scozzesi C, Bianchi M, von Andrian U, Chisari F, Guidotti L (2011). "Kupffer Cells Hasten Resolution of Liver Immunopathology in Mouse Models of Viral Hepatitis". PLOS Pathogens. DOI:10.1371/journal.ppat.1002061. PMID 21655107. PMC: 3107209. | ||
Author | Sitia G, Iannacone M, Aiolfi R, Isogawa M, van Rooijen N, Scozzesi C, Bianchi M, von Andrian U, Chisari F, Guidotti L | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 14:14, 17 November 2012 | 23 s, 320 × 238 (390 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Sitia G, Iannacone M, Aiolfi R, Isogawa M, van Rooijen N, Scozzesi C, Bianchi M, von Andrian U, Chisari F, Guidotti L |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2011-06 |