English: HBV replication-competent transgenic mice were injected with NaCl and 3 days later subjected to liver intravital microscopy. The movie depicts lobular liver sinusoids in a representative mouse that was infused 5 minutes earlier with 5×107 CFSE-labeled HBV-specific effector CD8 T cells. Analysis of movies derived from six independent HBV replication-competent transgenic mice revealed a sticking fraction (defined as the percentage of total CD8 T cells that became firmly adherent for ≥30 s while passing a liver sinusoid within a 30 minutes observation period) of 29.2%±3.1%. Note that the sticking fraction of effector CD8 T cells that were specific for an irrelevant antigen (LCMV) and were infused into HBV replication-competent transgenic mice was detected as less than 5% (not shown). Scale bar represents 50 µm.