File:Overcoming-Multidrug-Resistance-via-Photodestruction-of-ABCG2-Rich-Extracellular-Vesicles-pone.0035487.s004.ogv
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DescriptionOvercoming-Multidrug-Resistance-via-Photodestruction-of-ABCG2-Rich-Extracellular-Vesicles-pone.0035487.s004.ogv |
English: Photodestruction of EVs and gradual nuclear accumulation of C-1371 upon illumination of MCF-7/FLV1000 cells. MCF-7/FLV1000 cells were exposed to C-1371 (10 µM) for 24 h at 37°C to allow for its accumulation within EVs. Then, random fields were continuously exposed to blue light using the GFP+DsRED longpass filter and photographed each 5 seconds for a total of 120 cycles (a total of 10 min) using the Cell-Observer microscope at a ×630 magnification. The obtained time-lapse images were animated into a video using LSM image browser software (Zeiss Inc.). |
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Source | Movie S2 from Goler-Baron V, Assaraf Y (2012). "Overcoming Multidrug Resistance via Photodestruction of ABCG2-Rich Extracellular Vesicles Sequestering Photosensitive Chemotherapeutics". PLOS ONE. DOI:10.1371/journal.pone.0035487. PMID 22530032. PMC: 3329466. | ||
Author | Goler-Baron V, Assaraf Y | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 10:30, 15 November 2012 | 24 s, 1,344 × 1,024 (301 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Goler-Baron V, Assaraf Y |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
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Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2012 |