File:Phagocytic-Receptor-CED-1-Initiates-a-Signaling-Pathway-for-Degrading-Engulfed-Apoptotic-Cells-pbio.0060061.sv004.ogv
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Phagocytic-Receptor-CED-1-Initiates-a-Signaling-Pathway-for-Degrading-Engulfed-Apoptotic-Cells-pbio.0060061.sv004.ogv (Ogg Theora video file, length 18 s, 318 × 450 pixels, 664 kbps, file size: 1.39 MB)
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editDescriptionPhagocytic-Receptor-CED-1-Initiates-a-Signaling-Pathway-for-Degrading-Engulfed-Apoptotic-Cells-pbio.0060061.sv004.ogv |
English: In a rab-7(ok511) (m − z − ) Embryo, the Recruitment and Fusion of CTNS-1–Labeled Lysosomal Particles to Phagosomal Surface Are Both Defective This movie records the journey of a single CTNS-1(+) particle (arrow) towards a phagosome in a rab-7 embryo expressing Pced-1 ctns-1::gfp. Images captured in 2-min intervals are shown. It took the CTNS-1(+) particle 16 min to be recruited to phagosomal surface, which is significantly longer than what was observed in wild-type embryos, indicating a defect in recruitment. In addition, this CTNS-1(+) particle failed to fuse to phagosomal membrane after attachment, in a period of 52 min, indicating a fusion defect. |
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Source | Video S4 from Yu X, Lu N, Zhou Z (2008). "Phagocytic Receptor CED-1 Initiates a Signaling Pathway for Degrading Engulfed Apoptotic Cells". PLOS Biology. DOI:10.1371/journal.pbio.0060061. PMID 18351800. PMC: 2267821. | ||
Author | Yu X, Lu N, Zhou Z | ||
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This file is licensed under the Creative Commons Attribution 3.0 Unported license.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 00:43, 19 October 2016 | 18 s, 318 × 450 (1.39 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Short title | In a rab-7(ok511) (m − z − ) Embryo, the Recruitment and Fusion of CTNS-1–Labeled Lysosomal Particles to Phagosomal Surface Are Both Defective |
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Author | Yu X, Lu N, Zhou Z |
Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | This movie records the journey of a single CTNS-1(+) particle (arrow) towards a phagosome in a rab-7 embryo expressing Pced-1 ctns-1::gfp. Images captured in 2-min intervals are shown. It took the CTNS-1(+) particle 16 min to be recruited to phagosomal surface, which is significantly longer than what was observed in wild-type embryos, indicating a defect in recruitment. In addition, this CTNS-1(+) particle failed to fuse to phagosomal membrane after attachment, in a period of 52 min, indicating a fusion defect. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2008-03 |