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File:Rac1-mediated-signaling-plays-a-central-role-in-secretion-dependent-platelet-aggregation-in-human-1479-5876-8-128-S3.ogv

Rac1-mediated-signaling-plays-a-central-role-in-secretion-dependent-platelet-aggregation-in-human-1479-5876-8-128-S3.ogv ‎(Ogg Theora video file, length 41 s, 640 × 480 pixels, 220 kbps, file size: 1.06 MB)

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English: Movie S1. Effect of NSC23766 on human plaque-induced platelet thrombus formation under arterial flow conditions. Hirudin-anticoagulated blood was incubated with mepacrine to visualize platelets by fluorescence. Blood was perfused (direction right to left) over atherosclerotic plaque-coated microfluidic chambers and observed for 10 min. Upper channel, control; lower channel, blood pre-treated with 300 μM NSC23766. In the upper channel, rapid platelet adhesion and aggregate formation (green fluorescence) occurred, mainly at the edges of the channel, where also the majority of plaque material is present (as seen by phase contrast microscopy before start of the flow experiments). NSC23766 reduced platelet adhesion and aggregate formation. The video is in. mov format and can be viewed using Quick time player on different PCs with Windows XP or Vista.
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Source Dwivedi S, Pandey D, Khandoga A, Brandl R, Siess W (2010). "Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque". Journal of Translational Medicine. DOI:10.1186/1479-5876-8-128. PMID 21134286. PMC: 3018435.
Author Dwivedi S, Pandey D, Khandoga A, Brandl R, Siess W
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current11:23, 20 November 201241 s, 640 × 480 (1.06 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 480P 131 kbps Completed 20:09, 16 October 2018 36 s
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VP9 360P 67 kbps Completed 20:09, 16 October 2018 37 s
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VP9 240P 41 kbps Completed 20:09, 16 October 2018 26 s
Streaming 240p (VP9) 43 kbps Completed 09:28, 16 December 2023 1.0 s
WebM 360P 381 kbps Completed 11:26, 20 November 2012 59 s
Streaming 144p (MJPEG) 561 kbps Completed 05:07, 18 November 2023 3.0 s

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