File:Selective-anticancer-activity-of-a-hexapeptide-with-sequence-homology-to-a-non-kinase-domain-of-1476-4598-10-72-S1.ogv
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Selective-anticancer-activity-of-a-hexapeptide-with-sequence-homology-to-a-non-kinase-domain-of-1476-4598-10-72-S1.ogv (Ogg Theora video file, length 28 s, 400 × 250 pixels, 113 kbps, file size: 390 KB)
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editDescriptionSelective-anticancer-activity-of-a-hexapeptide-with-sequence-homology-to-a-non-kinase-domain-of-1476-4598-10-72-S1.ogv |
English: Time Lapse Photomicrographic Video of H460 human non-small lung cancer cells exposed in-vitro to 200 μM THR53. H460 cells were grown in the presence of 200 μM THR53 in Ham's F12 medium + 10% FCS. Micrographic video frames at ×40 magnification were taken at 20 minute intervals and are shown at 7 frames per second. In contrast to control H460 cells, grown in the same medium in the absence of THR53 (see below), although undergoing repeated cell divisions, treated H460 cells show progressive cell death throughout succesive divisions, typified by cellular swelling, vacuolation and disintegration. There is no morphological evidence of apoptosis. |
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Source | Warenius H, Kilburn J, Essex J, Maurer R, Blaydes J, Agarwala U, Seabra L (2011). "Selective anticancer activity of a hexapeptide with sequence homology to a non-kinase domain of Cyclin Dependent Kinase 4". Molecular Cancer. DOI:10.1186/1476-4598-10-72. PMID 21668989. PMC: 3126777. | ||
Author | Warenius H, Kilburn J, Essex J, Maurer R, Blaydes J, Agarwala U, Seabra L | ||
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This file is licensed under the Creative Commons Attribution 2.0 Generic license.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 17:05, 20 November 2012 | 28 s, 400 × 250 (390 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Short title | Additional file 1 |
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Author | Warenius H, Kilburn J, Essex J, Maurer R, Blaydes J, Agarwala U, Seabra L |
Usage terms | http://creativecommons.org/licenses/by/2.0/ |
Image title | |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2011 |