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File:Targeted-Proteolysis-of-Plectin-Isoform-1a-Accounts-for-Hemidesmosome-Dysfunction-in-Mice-Mimicking-pgen.1002396.s015.ogv

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English: Representative time lapse video showing migration of keratinocytes transiently expressing Ogna P1a. Migrating immortalized Plec+/+ keratinocytes expressing Ogna P1a-GFP were monitored using time-lapse video microscopy. Images were collected every 10 minutes for 12 hours. Note that GFP-fluorescence was only visualized during the first time frame and is shown at the start of the video. Only cells strongly expressing full length P1a (arrows) were used for determination of single cell migration velocities. Cells that had not yet fully spread (arrowhead 1), migrated out of the field of view during the period of observation (arrowhead 2), were displaying signs of senescence (arrowhead 3), or were expressing P1a only weakly (arrowhead 4) were not taken into account for measuring.
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Source Video S2 from Walko G, Vukasinovic N, Gross K, Fischer I, Sibitz S, Fuchs P, Reipert S, Jungwirth U, Berger W, Salzer U, Carugo O, Castañón M, Wiche G (2011). "Targeted Proteolysis of Plectin Isoform 1a Accounts for Hemidesmosome Dysfunction in Mice Mimicking the Dominant Skin Blistering Disease EBS-Ogna". PLOS Genetics. DOI:10.1371/journal.pgen.1002396. PMID 22144912. PMC: 3228830.
Author Walko G, Vukasinovic N, Gross K, Fischer I, Sibitz S, Fuchs P, Reipert S, Jungwirth U, Berger W, Salzer U, Carugo O, Castañón M, Wiche G
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This file is licensed under the Creative Commons Attribution 2.5 Generic license.
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This file was published in a Public Library of Science journal. Their website states that the content of all PLOS journals is published under the Creative Commons Attribution 4.0 license (or its previous version depending on the publication date), unless indicated otherwise.
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Date/TimeThumbnailDimensionsUserComment
current03:00, 19 November 201211 s, 1,388 × 1,040 (4.56 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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VP9 720P 935 kbps Completed 10:59, 21 October 2018 7.0 s
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VP9 480P 494 kbps Completed 10:59, 21 October 2018 6.0 s
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VP9 360P 299 kbps Completed 10:58, 21 October 2018 6.0 s
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VP9 240P 158 kbps Completed 10:58, 21 October 2018 4.0 s
Streaming 240p (VP9) 158 kbps Completed 10:41, 17 December 2023 1.0 s
WebM 360P 476 kbps Completed 05:01, 19 November 2012 7.0 s
Streaming 144p (MJPEG) 274 kbps Completed 03:27, 9 November 2023 1.0 s

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