File:Twisting-Right-to-Left-A…A-Mismatch-in-a-CAG-Trinucleotide-Repeat-Overexpansion-Provokes-Left-pcbi.1004162.s006.ogv
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Twisting-Right-to-Left-A…A-Mismatch-in-a-CAG-Trinucleotide-Repeat-Overexpansion-Provokes-Left-pcbi.1004162.s006.ogv (Ogg Theora video file, length 1 min 10 s, 372 × 372 pixels, 196 kbps, file size: 1.62 MB)
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DescriptionTwisting-Right-to-Left-A…A-Mismatch-in-a-CAG-Trinucleotide-Repeat-Overexpansion-Provokes-Left-pcbi.1004162.s006.ogv |
English: Base flipping leading to the formation of B-Z junction at A 11 …A 26 mismatch site in d(CAG) 6 .d(CAG) 6 DNA duplex with +syn…anti starting conformation for the mismatch ( Fig. 5A ). Note that prior to flipping, both the A’s are moving apart that results in total loss of hydrogen bond and subsequently, one of the A’s flips by rotating in clockwise direction. |
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Source | S6 Movie from Khan N, Kolimi N, Rathinavelan T (2015). "Twisting Right to Left: A…A Mismatch in a CAG Trinucleotide Repeat Overexpansion Provokes Left-Handed Z-DNA Conformation". PLOS Computational Biology. DOI:10.1371/journal.pcbi.1004162. PMID 25876062. PMC: 4395422. | ||
Author | Khan N, Kolimi N, Rathinavelan T | ||
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 23:29, 24 April 2015 | 1 min 10 s, 372 × 372 (1.62 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Short title | Base flipping leading to the formation of B-Z junction at A 11 …A 26 mismatch site in d(CAG) 6 .d(CAG) 6 DNA duplex with +syn…anti starting conformation for the mismatch ( Fig. 5A ). |
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Author | Khan N, Kolimi N, Rathinavelan T |
Usage terms | http://creativecommons.org/licenses/by/4.0/ |
Image title | Note that prior to flipping, both the A’s are moving apart that results in total loss of hydrogen bond and subsequently, one of the A’s flips by rotating in clockwise direction. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2015-04-13 |