Identifier: amaarchivesofneu08ameruoft (find matches)
Title: A. M. A. archives of neurology & psychiatry
Year: 1919 (1910s)
Authors: American Medical Association
Subjects: Neurology Psychiatry
Publisher: (Chicago) American Medical Association
Contributing Library: Gerstein - University of Toronto
Digitizing Sponsor: University of Toronto

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reach the meninges early inthe infection in a large proportion of cases of syphilis, but in mostcases they do not get a foothold in the parenchyma. They have beenshown, with the microscope, by various authors to exist in the spinalfluid in patients with early syphilis—not in those with general paralysis. D UXLA P—GEXERA L PARALYSIS 603 Again in early syphilis, untreated, about 80 per cent, of the patients,according to Sioli, who bases his figures on an extensive material col-lected from the literature, have shown an abnormal state of the spinalfluid, either in the Wassermann reaction, cell count, albumin contentor in some other manner. In the second stage of syphilis only about33 per cent, of the patients showed similiar changes in the fluid; inthe third stage and latent stage, about 23 per cent. So we can say thatin the early stages of syphilis changes in the spinal fluid are at leastfrequent, but that later the changes spontaneously disappear in manjcases and persist in others.
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Fig. 14.—Spirochetes in the wall of a blood vessel, also in the zone ofthe infiltrate, and one (A) within the lumen. The latter parasite probablyreached its position among the corpuscles after death. IS GENERAL PARALYSIS CAUSED BY A SPECIAL STRAIX OF SPIROCHETE, A NEUROTROPIC STRAIX, DIFFERENT AT THE BEGINNING FROM THE SPIROCHETE OF ORDINARY SYPHILIS? In favor of this view are groups of patients with general paralysisand tabes infected from the same source: cases of conjugal infectionin which husband and wife both have general paralysis of tabes; infec-tions among members of the same familv who develop general paralysisor tabes. 604 ARCfllJES OF XEUROLOGY AM) PSVCIILirRV To balance such facts is a report of group infection, likewise froma common source (Eichelberg, re))orted by Sioli), in which all of theinfected members, thirteen in number, developed ordinary syphilisexcept two; one of these develojied general jjaralysis, the other tabes. Certain writers, especially Levaditi and Ma

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