Identifier: americanpractice03brya (find matches)
Title: American practice of surgery : a complete system of the science and art of surgery
Year: 1906 (1900s)
Authors: Bryant, Joseph D. (Joseph Decatur), 1845-1914 Buck, Albert H. (Albert Henry), 1842-1922
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Publisher: New York : W. Wood and company
Contributing Library: University of California Libraries
Digitizing Sponsor: Internet Archive

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albumoses in the urine, and asecond by Weber, in 1867. In all, upto the present date, about 40 cases have been reported, many having been described during the past year. Someobservers include under this designation a larger number of cases than a rigidscrutiny would seem to permit. Their pathological descriptions are often-times brief and unsatisfactory. (See Fig. 198.) Etiology.—The etiology of multiple myeloma is as obscure as that of otherhyperplastic conditions in the bone marrow, yet toxic agents appear to playa certain role. Men, usually of the working classes, are more commonly affectedthan women, the disease appearing in most instances between the ages of 40 and50. The oldest case reported was that of a man 70 years old, the youngest awoman of 36. Syphilis has no important bearing on the disease, and, when itoccurs in women, it has no relation to pregnancy or the puerperium. In 2 ofthe reported cases there was some question of heredity, one having had a brothervol. in.—30
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Fig. 205.—Osteoid Sarcoma of the Head of theTibia. (Massachusetts General Hospital.) 466 AMERICAN PRACTICE OF SURGERY. die of a similar disease, while the other lost a daughter of pernicious anaemia.As to trauma, out of 24 cases a history of some kind of injury was given in only4, and in 2 of these the injury was inflicted many years previous to the appear-ance of the symptoms (Hoffmann). The possibility of its infectious origin hasalso been considered, and in support of this theory are the changes in the bone marrow known to take place in certaininfectious diseases and after poisoningwith arsenic. Furthermore, as the tu-mors are formed of plasma cells, theyresemble greatly many of the so-calledinfectious granulomata. Pathological Anatomy.—The primarychanges found post mortem have in allcases been limited to the bones, theother portions of the body being nor-mal except for the changes that onewould expect to find in any case ofsecondary anaemia of a high grade andthose due to mech

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