Identifier: endocrinology07asso (find matches)
Title: Endocrinology
Year: 1917 (1910s)
Authors: Association for the Study of Internal Secretions (U.S.) Endocrine Society
Subjects: Endocrinology Endocrinology
Publisher: Los Angeles, Calif. : Association for the Study of Internal Secretions
Contributing Library: Gerstein - University of Toronto
Digitizing Sponsor: University of Toronto

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mation ofSteinachs feminization was found. The anatomical conditions of the tran.splants showed thatit is possible to get only a relative isolation of the ovary ele-ments by a more or less complete elimination of one or two ofthese elements. Most freciuently all three were found; as arule corpora lutea dominated the picture together with often 290 ENDOCRINOLOGY OF SEXUAL GLANDS only insignificant quantities of the other tissues; the least resist-ant-were the follicles. The heterological isotransplants partly showed a remnant,most frequently not well preserved, and partly gave the infor-mation that the follicles in the heterological organism can, ofcourse, develop into mat»rity but more often tend toward atresia,so that the theca lutein tissue is increased; on the other hand,maturing with subsecjuent corpus luteum formation, as found in Fig. 15Microphotograph (mafled the same as Fig.shows papillae mammaa normal female in \iperio. In the underltissue large conglomernof glandular tissua
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auto- and iso-transplants, almost the same as in normal ovaries,only very seldom takes place. A comparison between the hormone effects in transplants,their approximate number (they were measured by micrometry)and their contents of the three ovarian elements showed that asmall quantity of all three elements can be found without anytraceable hormone effect. Quantitative laws seem to rule: inorder to produce a hormone effect a certain minimal quantityof ovarian tissue is required. In transplantings with plentiful SAND 291 ovarian tissue with normal hormone effect, widely different com-binations, in (juantity and kind, of the three elements werefound. On the whole the results of my experiments in 1914-17did not indicate the production of the female sexual hormonesin any single one of the ovary elements, but supported, in thehighest degree, the latest views, especially in the form put forthby Bucura, according to which the three elements, morpho-logically and physiologically, must be seen

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