Identifier: breastitsanomali00deav (find matches)
Title: The breast: its anomalies, its diseases, and their treatment
Year: 1917 (1910s)
Authors: Deaver, John B. (John Blair), 1855-1931
Subjects: Breast Breast X-rays Breast Diseases Breast Neoplasms Radiotherapy
Publisher: Philadelphia, P. Blakiston's Son & Co
Contributing Library: Francis A. Countway Library of Medicine
Digitizing Sponsor: Open Knowledge Commons

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the stroma, and is variegated, being finely mottled with pink and tan, the generaleffect being to darken the tissue and make it contrast with the normal white of the mam-mary tissue. The degree of mottling and variegation depends in large measure upon thevarying proportions of cellular and intercellular components in the cancer. In scirrhus, CARCINOMA 491 where the connective tissue stroma preponderates, it is far less marked than in encepha-loid or adeno-carcinoma in which the cellular structure preponderates. The analysis of the variegated appearance resolves it into the whitish or grayishstroma, the pinkish healthy cellular tissue, the tan color of necrotic cells and the reddots of gaping transversely cut blood-vessels. When the tumor is larger and can at once be felt and found when the breast is handled,the same general description applies, though now the growth may have progressed to apoint when it takes on one of the forms sufficiently well characterized to constitute avariety.
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Fig. 182.—Pigmented squamous cell carcinoma, mistaken clinically for melanotic sarcoma.(High power.) Scirrhus.—In typical cases of scirrhus carcinoma, the breast is small and hard, or ifit be large because it contains much adipose tissue, it presents a hard body of indefiniteshape. When incised, the tissue is tough and dense almost like leather, the cut surfacepresenting an appearance like a dense scar. The confines of the cancer are usually notdeUmited. The scar-like tumor tissue usually extends irregularly in this direction andthat, and as it contains comparatively little cellular tissue, is but slightly variegated inappearance, and little darker in color than the breast tissue itself. In some cases moreor less distinct nodules with fairly clear separation from the white mammary tissue, andmuch more sharp separation from the yellow fat show a pinkish color. In such the type 492 THE BREAST of the tumor is much less clearly shown upon microscopic examination than in the densermore

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