Identifier: breastitsanomali00deav (find matches)
Title: The breast: its anomalies, its diseases, and their treatment
Year: 1917 (1910s)
Authors: Deaver, John B. (John Blair), 1855-1931
Subjects: Breast Breast X-rays Breast Diseases Breast Neoplasms Radiotherapy
Publisher: Philadelphia, P. Blakiston's Son & Co
Contributing Library: Francis A. Countway Library of Medicine
Digitizing Sponsor: Open Knowledge Commons

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any parallel incisions and carefully feeling the tissue forindurations. The normal white mammary tissue is soft and yielding to the fingers, can-cer tissue is usually firm and hard: In the routine examination of a breast every areaof dense texture should be carefully incised and examined. It has been a rare happening 49° THE BREAST in our experience for cancer tissue to be discovered by microscopic examination withoutpreviously having been detected by the finger or the eye. The cut surface of the denser cancer tissue usually presents an appearance, which,varying somewhat in the different varieties of cancer, is sufficiently different from thenormal to attract the eye. In general, it may be said to present a drawn and variegatedappearance. The area may be fairly well defined, but is rarely sharply circumscribedand never encapsulated. As a rule, it tends to fade away on all sides by irregular exten-sions into the surrounding healthy tissue. The more localized the lesion is, the more it
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Fig. i8i.—Pigmented squamous-cell carcinoma, mistaken clinically for melanotic sarcoma.(Low magnification.) tends to exhibit an appearance of radiation from a vague center; the more diffused it is,the more it shows linear striation and prolonged extensions that draw upon the adjacentglandular tissue. This drawn appearance, for which the interstitial connective tissueor stroma is responsible is sometimes secondary in importance to the color change thoughit may exceed it. The tissue frequently looks somewhat porous, the pores being thespaces in the stroma, and is variegated, being finely mottled with pink and tan, the generaleffect being to darken the tissue and make it contrast with the normal white of the mam-mary tissue. The degree of mottling and variegation depends in large measure upon thevarying proportions of cellular and intercellular components in the cancer. In scirrhus, CARCINOMA 491 where the connective tissue stroma preponderates, it is far less marked than in encepha-lo

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